• Serves as a one-stop resource for key concepts and information on head and neck imaging, including disease identification, imaging techniques, and details on tumor staging and classification
• Reflects recent updates in genetic and molecular characterization of tumors, congenital malformations, and inflammatory/autoimmune disorders, which all have implications for targeted precision therapies
• Offers more than 400 concise, informative chapters, dividing content into sections based on head and neck spaces and anatomic regions, with additional sections on cancers, posttreatment appearances, pediatric lesions, and syndromic diseases
• Features more than 2,800 high-quality print images (with an additional 3,800 images in the complimentary eBook), including radiologic images, full-color medical illustrations, clinical photographs, histologic images, and gross pathologic photographs
• Provides new and expanded content on genomic characterization of head and neck cancers; new characterizations of sinonasal tract and skull base tumors through distinctive genetic and molecular signatures (as reflected in the WHO’s 2022 reclassification); newer imaging techniques to characterize neuroendocrine tumors and spread using DOTATATE PET; whole-body imaging surveillance strategies for Li-Fraumeni syndrome, hereditary paraganglioma pheochromocytomas, and hereditary retinoblastoma; and the use of whole-body MR for tumor syndromes, multifocal vascular anomalies, and much more
• Emphasizes multidisciplinary involvement to help radiologists navigate the intersection of multiple specialties and confidently guide a wide variety of clinicians and surgeons to the appropriate diagnosis and treatment for a multitude of disorders
• Uses bulleted, succinct text and highly templated chapters for quick comprehension of essential information at the point of care
• Includes an eBook that allows you access to everything in the print version as well as additional images, text, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud; additional digital ancillary content may publish up to 6 weeks following the publication date

Part I: Introduction and Overview of Suprahyoid and Infrahyoid Neck

Suprahyoid and Infrahyoid Neck Overview

Part II: Parapharyngeal Space

Parapharyngeal Space Overview

Section 1: Benign Tumors

Parapharyngeal Space Benign Mixed Tumor

Part III: Pharyngeal Mucosal Space

Pharyngeal Mucosal Space Overview

Section 1: Congenital Lesions

Tornwaldt Cyst

Section 2: Infectious and Inflammatory Lesions

Retention Cyst of Pharyngeal Mucosal Space
Tonsillar Inflammation
Tonsillar/Peritonsillar Abscess

Section 3: Benign and Malignant Tumors

Pleomorphic Adenoma of Pharyngeal Mucosal Space
Minor Salivary Gland Malignancy of Pharyngeal Mucosal Space
Non-Hodgkin Lymphoma of Pharyngeal Mucosal Space

Part IV: Masticator Space

Masticator Space Overview

Section 1: Pseudolesions

Pterygoid Venous Plexus Asymmetry
Benign Masticator Muscle Hypertrophy
CNV3 Motor Denervation

Section 2: Infectious Lesions

Masticator Space Abscess

Section 3: Benign Tumors

Masticator Space CNV3 Schwannoma

Section 4: Malignant Tumors

Masticator Space CNV3 Perineural Tumor
Masticator Space Chondrosarcoma
Masticator Space Sarcoma

Part V: Parotid Space

Parotid Space Overview

Section 1: Infectious and Inflammatory Lesions

Acute Parotitis
Parotid Sjögren Syndrome
Benign Lymphoepithelial Cysts of HIV

Section 2: Benign Tumors

Parotid Pleomorphic Adenoma
Warthin Tumor
Parotid Schwannoma

Section 3: Malignant Tumors

Parotid Mucoepidermoid Carcinoma
Parotid Adenoid Cystic Carcinoma
Parotid Acinic Cell Carcinoma
Parotid Mammary Analogue Secretory Carcinoma
Parotid Malignant Mixed Tumor
Parotid Non-Hodgkin Lymphoma
Metastatic Disease of Parotid Nodes

Part VI: Carotid Space

Carotid Space Overview

Section 1: Normal Variants

Tortuous Carotid Artery in Neck

Section 2: Vascular Lesions

Carotid Artery Dissection in Neck
Carotid Artery Pseudoaneurysm in Neck
Carotid Artery Fibromuscular Dysplasia in Neck
Acute Idiopathic Carotidynia
Jugular Vein Thrombosis
Postpharyngitis Venous Thrombosis (Lemierre)

Section 3: Benign Tumors

Carotid Body Paraganglioma
Vagal Paraganglioma
Carotid Space Schwannoma
Sympathetic Schwannoma
Carotid Space Neurofibroma
Carotid Space Meningioma

Part VII: Retropharyngeal Space

Retropharyngeal Space Overview

Section 1: Infectious and Inflammatory Lesions

Reactive Adenopathy of Retropharyngeal Space
Suppurative Adenopathy of Retropharyngeal Space
Retropharyngeal Space Abscess
Retropharyngeal Space Edema

Section 2: Metastatic Tumors

Nodal Squamous Cell Carcinoma of Retropharyngeal Space
Nodal Non-Hodgkin Lymphoma in Retropharyngeal Space
Non-Squamous Cell Carcinoma Metastatic Nodes in Retropharyngeal Space

Part VIII: Perivertebral Space

Perivertebral Space Overview

Section 1: Pseudolesions

Levator Scapulae Muscle Hypertrophy

Section 2: Infectious and Inflammatory Lesions

Acute Calcific Longus Colli Tendonitis
Perivertebral Space Infection

Section 3: Vascular Lesions

Vertebral Artery Dissection in Neck

Section 4: Benign and Malignant Tumors

Brachial Plexus Schwannoma in Perivertebral Space
Chordoma in Perivertebral Space
Vertebral Body Metastasis in Perivertebral Space

Part IX: Posterior Cervical Space

Posterior Cervical Space Overview

SECTION 1: BENIGN TUMORS

Posterior Cervical Space Schwannoma

Section 2: Metastatic Tumors

Squamous Cell Carcinoma in Spinal Accessory Node
Non-Hodgkin Lymphoma in Spinal Accessory Node

Part X: Visceral Space

Visceral Space Overview

Section 1: Inflammatory Lesions

Chronic Lymphocytic Thyroiditis (Hashimoto)

Section 2: Metabolic Disease

Multinodular Goiter

Section 3: Benign Tumors

Thyroid Adenoma
Parathyroid Adenoma in Visceral Space

Section 4: Malignant Tumors

Differentiated Thyroid Carcinoma
Medullary Thyroid Carcinoma
Anaplastic Thyroid Carcinoma
Non-Hodgkin Lymphoma of Thyroid
Parathyroid Carcinoma
Thyroglossal Duct Cyst Carcinoma
Cervical Esophageal Carcinoma

Section 5: Miscellaneous

Esophagopharyngeal Diverticulum (Zenker)
Colloid Cyst of Thyroid
Lateral Cervical Esophageal Diverticulum

Part XI: Hypopharynx, Larynx, and Cervical Trachea

Hypopharynx, Larynx, and Trachea Overview

Section 1: Infectious and Inflammatory Lesions

Croup
Epiglottitis in Child
Supraglottitis

Section 2: Trauma

Laryngeal Trauma

Section 3: Benign and Malignant Tumors

Upper Airway Infantile Hemangioma
Laryngeal Chondrosarcoma

Section 4: Treatment-Related Lesions

Postradiation Larynx

Section 5: Miscellaneous

Laryngocele
Vocal Cord Paralysis
Acquired Subglottic-Tracheal Stenosis

Part XII: Lymph Nodes

Lymph Node Overview

Section 1: Infectious and Inflammatory Lesions

Reactive Lymph Nodes
Suppurative Lymph Nodes
Tuberculous Lymph Nodes
Nontuberculous Mycobacterium Nodes
Sarcoidosis Lymph Nodes
Giant Lymph Node Hyperplasia (Castleman Disease)
Histiocytic Necrotizing Lymphadenitis (Kikuchi- Fujimoto)
Kimura Disease

Section 2: Malignant Tumors

Nodal Hodgkin Lymphoma in Neck
Nodal Non-Hodgkin Lymphoma in Neck
Nodal Differentiated Thyroid Carcinoma
Systemic Nodal Metastases in Neck

Part XIII: Transspatial and Multispatial

Transspatial and Multispatial Overview

Section 1: Normal Variants

Prominent Thoracic Duct in Neck

Section 2: Benign Tumors

Lipoma of Head and Neck
Solitary Fibrous Tumor/Hemangiopericytoma
Plexiform Neurofibroma of Head and Neck

Section 3: Malignant Tumors

Posttransplantation Lymphoproliferative Disorder
Extraosseous Chordoma
Non-Hodgkin Lymphoma of Head and Neck
Liposarcoma of Head and Neck
Synovial Sarcoma of Head and Neck
Malignant Peripheral Nerve Sheath Tumor of Head and Neck

Section 4: Miscellaneous

Lymphocele of Neck
Sinus Histiocytosis (Rosai-Dorfman) of Head and Neck
Fibromatosis of Head and Neck
IgG4-Related Disease
COVID-19

Part XIV: Oral Cavity

Oral Cavity Overview

Section 1: Pseudolesions

Hypoglossal Nerve Motor Denervation

Section 2: Congenital Lesions

Submandibular Space Accessory Salivary Tissue
Oral Cavity Dermoid and Epidermoid
Oral Cavity Lymphatic Malformation
Lingual Thyroid

Section 3: Infectious and Inflammatory Lesions

Ranula
Oral Cavity Sialocele
Submandibular Gland Sialadenitis
Oral Cavity Abscess

Section 4: Benign Tumors

Submandibular Gland Benign Mixed Tumor
Palate Benign Mixed Tumor

Section 5: Malignant Tumors

Sublingual Gland Carcinoma
Submandibular Gland Carcinoma
Oral Cavity Minor Salivary Gland Malignancy
Submandibular Space Nodal Non-Hodgkin Lymphoma
Submandibular Space Nodal Squamous Cell Carcinoma

Part XV: Mandible-Maxilla and TMJ

Mandible-Maxilla and TMJ Overview

Section 1: Congenital LESIONS

Solitary Median Maxillary Central Incisor

Section 2: Nonneoplastic Cysts

Nasolabial Cyst
Periapical Cyst (Radicular)
Dentigerous Cyst
Simple Bone Cyst (Traumatic)
Nasopalatine Duct Cyst

Section 3: Infectious and Inflammatory Lesions

TMJ Juvenile Idiopathic Arthritis
Mandible-Maxilla Osteomyelitis

Section 4: Tumor-Like Lesions

TMJ Calcium Pyrophosphate Dihydrate Deposition Disease
TMJ Pigmented Villonodular Synovitis
TMJ Synovial Chondromatosis
Mandible-Maxilla Central Giant Cell Granuloma

Section 5: Benign and Malignant Tumors

Ameloblastoma
Odontogenic Keratocyst
Mandible-Maxilla Osteosarcoma

Section 6: Treatment-Related Lesions

Medication-Related Osteonecrosis of Jaw (MRONJ)

Part XVI: Introduction and Overview of Squamous Cell Carcinoma

Squamous Cell Carcinoma Overview

Part XVII: Primary Sites, Perineural Tumor and Nodes

SECTION 1: NASOPHARYNGEAL
CARCINOMA
Nasopharyngeal Carcinoma

Section 2: Oropharyngeal Carcinoma

Base of Tongue Squamous Cell Carcinoma
Palatine Tonsil Squamous Cell Carcinoma
Posterior Oropharyngeal Wall Squamous Cell Carcinoma
HPV-Related Oropharyngeal Squamous Cell Carcinoma
Soft Palate Squamous Cell Carcinoma

Section 3: Oral Cavity Carcinoma

Oral Tongue Squamous Cell Carcinoma
Floor of Mouth Squamous Cell Carcinoma
Alveolar Ridge Squamous Cell Carcinoma
Retromolar Trigone Squamous Cell Carcinoma
Buccal Mucosa Squamous Cell Carcinoma
Hard Palate Squamous Cell Carcinoma

Section 4: Hypopharyngeal Carcinoma

Pyriform Sinus Squamous Cell Carcinoma
Postcricoid Hypopharynx Squamous Cell Carcinoma
Posterior Hypopharyngeal Wall Squamous Cell Carcinoma

Section 5: Laryngeal Carcinoma

Supraglottic Laryngeal Squamous Cell Carcinoma
Glottic Laryngeal Squamous Cell Carcinoma
Subglottic Laryngeal Squamous Cell Carcinoma
Laryngeal Squamous Cell Carcinoma With Secondary Laryngocele

Section 6: Perineural Tumor

Perineural Tumor Spread

Section 7: Squamous Cell Carcinoma Lymph Nodes

Nodal Squamous Cell Carcinoma

Part XVIII: Posttreatment Neck

Nodal Dissection in Neck
Reconstruction Flaps in Neck
Expected Changes of Neck Radiation Therapy
Complications of Neck Radiation Therapy
Osteoradionecrosis
Post Laryngectomy

Part XIX: Pediatric Lesions

Approach to Congenital Cystic Neck Masses

Section 1: Congenital Lesions

Lymphatic Malformation
Venous Malformation
Congenital Vallecular Cyst
Thyroglossal Duct Cyst
Cervical Thymic Cyst
1st Branchial Cleft Cyst
2nd Branchial Cleft Cyst
3rd Branchial Cleft Cyst
4th Branchial Cleft Cyst
Dermoid and Epidermoid Cysts

Section 2: Benign Tumors and Tumor-Like Lesions

Infantile Hemangioma
Fibromatosis Colli

Section 3: Malignant Tumors

Rhabdomyosarcoma
Primary Cervical Neuroblastoma
Metastatic Neuroblastoma

Part XX: Syndromic Diseases

Neurofibromatosis Type 1
Schwannomatosis
Neurofibromatosis Type 2
Basal Cell Nevus Syndrome
Branchiootorenal Syndrome
CHARGE Syndrome
Hemifacial Microsomia
Treacher Collins Syndrome
Pierre Robin Sequence
X-Linked Stapes Gusher (DFNX2)
McCune-Albright Syndrome
Cherubism
Mucopolysaccharidosis

Part XXI: Nose and Sinus

Sinonasal Overview

Section 1: Congenital Lesions

Nasolacrimal Duct Mucocele
Choanal Atresia
Nasal Glioma
Nasal Dermal Sinus
Frontoethmoidal Cephalocele
Congenital Nasal Pyriform Aperture Stenosis

Section 2: Infectious and Inflammatory Lesions

Acute Rhinosinusitis
Chronic Rhinosinusitis
Complications of Rhinosinusitis
Allergic Fungal Sinusitis
Sinus Mycetoma
Invasive Fungal Sinusitis
Sinonasal Polyposis
Solitary Sinonasal Polyp
Sinonasal Mucocele
Sinonasal Organized Hematoma
Silent Sinus Syndrome
Granulomatosis With Polyangiitis (Wegener)
Nasal Cocaine Necrosis

Section 3: Benign Tumors and Tumor-Like Lesions

Sinonasal Fibrous Dysplasia
Sinonasal Osteoma
Sinonasal Ossifying Fibroma
Juvenile Angiofibroma
Sinonasal Inverted Papilloma
Sinonasal Hemangioma
Sinonasal Nerve Sheath Tumor
Sinonasal Benign Mixed Tumor
Sinonasal Hamartomas
Sinonasal Glomangiopericytoma

Section 4: Malignant Tumors

Sinonasal Squamous Cell Carcinoma
Esthesioneuroblastoma
Sinonasal Melanoma
Sinonasal Adenocarcinoma
Sinonasal Non-Hodgkin Lymphoma
Sinonasal Neuroendocrine Carcinoma
Sinonasal Undifferentiated Carcinoma
Sinonasal Adenoid Cystic Carcinoma
Sinonasal Chondrosarcoma
Sinonasal Osteosarcoma
Sinonasal NUT Carcinoma
Sinonasal SWI/SNF Complex-Deficient Carcinoma
Sinonasal Biphenotypic Sarcoma
Sinonasal HIV-Associated Multiphenotypic Carcinoma

Part XXII: Orbit

Orbit Overview

Section 1: Congenital Lesions

Coloboma
Persistent Hyperplastic Primary Vitreous
Coats Disease
Orbital Dermoid and Epidermoid
Orbital Neurofibromatosis Type 1SECTION 2: VASCULAR LESIONS
Orbital Lymphatic Malformation
Orbital Venous Varix
Orbital Cavernous Venous Malformation (Hemangioma)

Section 3: Infectious and Inflammatory Lesions

Ocular Toxocariasis
Orbital Subperiosteal Abscess
Orbital Cellulitis
Idiopathic Orbital Inflammation (Pseudotumor)
Orbital Sarcoidosis
Thyroid-Associated Orbitopathy
Optic Neuritis

Section 4: Tumor-Like Lesions

Orbital Langerhans Cell Histiocytosis

Section 5: Benign Tumors

Orbital Infantile Hemangioma
Optic Pathway Glioma
Optic Nerve Sheath Meningioma
Lacrimal Gland Benign Mixed Tumor

Section 6: Malignant Tumors

Retinoblastoma
Ocular Melanoma
Orbital Lymphoproliferative Lesions
Lacrimal Gland Carcinoma

Part XXIII: Skull Base Lesions

Skull Base Overview

Section 1: Clivus

Ecchordosis Physaliphora
Fossa Navicularis Magna
Invasive Pituitary Macroadenoma
Chordoma

Section 2: Sphenoid Bone

Persistent Craniopharyngeal Canal
Sphenoid Benign Fatty Lesion
Central Skull Base Trigeminal Schwannoma

Section 3: Occipital Bone

Hypoglossal Nerve Schwannoma
Benign Enhancing Foramen Magnum Lesion

Section 4: Jugular Foramen

Jugular Bulb Pseudolesion
High Jugular Bulb
Dehiscent Jugular Bulb
Jugular Bulb Diverticulum
Jugulare Paraganglioma
Jugular Foramen Schwannoma
Jugular Foramen Meningioma

Section 5: Dural Sinuses

Dural Sinus and Aberrant Arachnoid Granulations
Skull Base Dural Sinus Thrombosis
Cavernous Sinus Thrombosis
Dural Arteriovenous Fistula

Section 6: Diffuse or Multifocal Skull Base Disease

Skull Base Cephalocele
Skull Base CSF Leak
Skull Base Fibrous Dysplasia
Skull Base Paget Disease
Skull Base Langerhans Cell Histiocytosis
Skull Base Osteopetrosis
Skull Base Giant Cell Tumor
Skull Base Meningioma
Skull Base Plasmacytoma
Skull Base Multiple Myeloma
Skull Base Metastasis
Skull Base Chondrosarcoma
Skull Base Osteosarcoma
Skull Base Osteomyelitis

Part XXIV: Skull Base, Facial, and Temporal Bone Trauma

Skull Base and Facial Trauma Overview

Section 1: Skull Base and Temporal Bone

Temporal Bone Fractures
Ossicular Dislocations and Disruptions
Skull Base Trauma

Section 2: Facial Bones

Orbital Foreign Body
Orbital Blowout Fracture
Transfacial Fractures (Le Fort)
Zygomaticomaxillary Complex Fracture
Complex Facial Fracture
Nasoorbitoethmoid (NOE) Fracture
Mandible Fracture
TMJ Disc Displacement

Part XXV: Temporal Bone

Temporal Bone Overview

Section 1: External Auditory Canal

CONGENITAL LESIONS

Foramen Tympanicum
Congenital External and Middle Ear Malformation

INFECTIOUS AND INFLAMMATORY LESIONS

Necrotizing External Otitis
Keratosis Obturans
Medial Canal Fibrosis
EAC-Acquired Cholesteatoma

BENIGN AND MALIGNANT TUMORS

EAC Osteoma
EAC Exostoses
EAC Skin Squamous Cell Carcinoma

Section 2: Middle Ear-Mastoid

CONGENITAL LESIONS

Congenital Middle Ear Cholesteatoma
Congenital Mastoid Cholesteatoma
Oval Window Atresia
Lateralized Internal Carotid Artery
Aberrant Internal Carotid Artery
Persistent Stapedial Artery

INFECTIOUS AND INFLAMMATORY LESIONS

Coalescent Otomastoiditis With Complications
Chronic Otomastoiditis With Ossicular Erosions
Chronic Otomastoiditis With Tympanosclerosis
Pars Flaccida Cholesteatoma
Pars Tensa Cholesteatoma
Mural Cholesteatoma
Middle Ear Cholesterol Granuloma

BENIGN AND MALIGNANT TUMORS

Tympanicum Paraganglioma
Temporal Bone Meningioma
Middle Ear Schwannoma
Middle Ear Adenoma
Temporal Bone Rhabdomyosarcoma

MISCELLANEOUS

1206 Temporal Bone Cephalocele
1208 Ossicular Prosthesis

Section 3: Inner Ear

PSEUDOLESIONS

Petromastoid Canal
Cochlear Cleft

CONGENITAL LESIONS

Labyrinthine Aplasia
Cochlear Aplasia
Cochlear Hypoplasia
Common Cavity Malformation
Cystic Cochleovestibular Malformation (IP-I)
Cochlear Incomplete Partition Type I (IP-I)
Cochlear Incomplete Partition Type II (IP-II)
Large Vestibular Aqueduct
Cochlear Nerve and Cochlear Nerve Canal Aplasia-Hypoplasia
Semicircular Canal Hypoplasia-Aplasia
Semicircular Canal-Vestibule Globular Anomaly

INFECTIOUS AND INFLAMMATORY LESIONS

1244 Labyrinthitis
1246 Otosyphilis
1248 Labyrinthine Ossificans
1252 Otosclerosis
1256 Temporal Bone Osteogenesis Imperfecta

BENIGN AND MALIGNANT TUMORS

1258 Intralabyrinthine Schwannoma
1262 Endolymphatic Sac Tumor

MISCELLANEOUS

1264 Intralabyrinthine Hemorrhage
1266 Semicircular Canal Dehiscence
1268 Cochlear Implant

Section 4: Petrous Apex

PSEUDOLESIONS

Petrous Apex Asymmetric Marrow
Petrous Apex Cephalocele

CONGENITAL LESIONS

Congenital Petrous Apex Cholesteatoma

INFECTIOUS AND INFLAMMATORY LESIONS

Petrous Apex Trapped Fluid
Petrous Apex Mucocele
Petrous Apex Cholesterol Granuloma
Apical Petrositis

VASCULAR LESIONS

Petrous Internal Carotid Artery Aneurysm

Section 5: Intratemporal Facial Nerve

PSEUDOLESIONS

Intratemporal Facial Nerve Enhancement
Middle Ear Prolapsing Facial Nerve

INFECTIOUS AND INFLAMMATORY LESIONS

Bell Palsy

BENIGN AND MALIGNANT TUMORS

Temporal Bone Facial Nerve Venous Malformation (Hemangioma)
Temporal Bone Facial Nerve Schwannoma
Temporal Bone Perineural Parotid Malignancy

Section 6: Temporal Bone, No Specific Anatomic Location

Temporal Bone CSF Leak
Temporal Bone Arachnoid Granulations
Temporal Bone Fibrous Dysplasia
Temporal Bone Paget Disease
Temporal Bone Langerhans Cell Histiocytosis
Temporal Bone Metastasis
Temporal Bone Osteoradionecrosis

Part XXVI: CPA-IAC

Section 1: Introduction and Overview

CPA-IAC Overview

Section 2: Congenital Lesions

CPA-IAC Epidermoid Cyst
CPA-IAC Arachnoid Cyst
Lipoma in CPA-IAC
IAC Venous Malformation

Section 3: Infectious and Inflammatory Lesions

CPA-IAC Meningitis
Ramsay Hunt Syndrome
CPA-IAC Neurosarcoid

Section 4: Benign and Malignant Tumors

Vestibular Schwannoma
PHACE(S) Syndrome
CPA-IAC Meningioma
CPA-IAC Facial Nerve Schwannoma
CPA-IAC Metastases

Section 5: Vascular Lesions

Trigeminal Neuralgia
Hemifacial Spasm
CPA-IAC Aneurysm
CPA-IAC Superficial Siderosis