- Offers investigative techniques written by an experienced team of active clinicians
- Provides both a patient-centred and specialty-centred approach to investigation of symptoms and signs, with advice on all relevant tests and the pitfalls of interpreting results
- Extensively illustrated to aid understanding of the more complex investigations and interpretation of results
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- Includes molecular and rapid diagnostics in infectious diseases, including PCR-based assays, MALDI-TOF, and updated antimicrobial resistance testing
- Offers advanced imaging techniques such as cardiovascular MRI and CT, oscillometry and exhaled nitric oxide in respiratory medicine, and hybrid PET/CT and PET/MRI in oncology and neurology
- Updated renal investigations, including CKD-EPI equations for GFR, modern approaches to proteinuria, and assessment of renal bone disease
- Expanded immunology and haematology sections, with new coverage of CAR-T monitoring, serum free light chains, reticulocyte Hb content, and next-generation molecular and flow cytometric assays
- Modernized toxicology and overdose management, reflecting new analytical techniques (LC-MS/MS) and protocols for medicolegal sampling
